The parameters specified may have created an excessive number of bins in space and time during the cube aggregation process. This has resulted in a large number of bins that contain no data and bins that may have no temporal neighbors, which will affect the results of your analysis. This may also cause a situation where the tool is unable to complete due to memory overflow.
You might consider using either a larger Distance Interval or a larger Time Step Interval. It is a good idea to aim for parameter settings that ensure the majority of bins contain data.