ArcGIS Pro 3.4 API Reference Guide
ArcGIS.Desktop.Layouts Namespace / LayoutView Class / DeactivateMapFrame Method
Example Version

DeactivateMapFrame Method
Deactivate the ActivatedMapFrame on the layout view. This method must be called on the UI thread.
Syntax
public void DeactivateMapFrame()
Exceptions
ExceptionDescription
Needs to run on the GUI thread
Layout view must be the active view
Remarks
This method must be called on the UI thread (and not the MCT as is most commonly the case with most other synchronous API methods) or an System.InvalidOperationException will be thrown. The layout view you are deactivating the ActivatedMapFrame "on" must be the current active view or an System.InvalidOperationException will be thrown. The deactivated map frame will remain selected.
Example
Deactivate Map Frame
//The active view must be a layout view.
var lv = LayoutView.Active;
if (lv == null)
  return;
var layout = lv.Layout;
if (layout == null)
  return;

//Deactivate any activated map frame
//Note: we are on the UI thread!
lv.DeactivateMapFrame();//no-op if nothing activated

//or - check if a  map frame is activated first...
if (lv.ActivatedMapFrame != null)
  //Note: we are on the UI thread!
  lv.DeactivateMapFrame();
Requirements

Target Platforms: Windows 11, Windows 10

ArcGIS Pro version: 3.1 or higher.
See Also