Description
The Integrate tool does not support feature classes that participate in a topology. Every topology has a specific cluster tolerance that is used in topological processing operations.
Solution
Consider validating the topology instead. As with the Integrate tool, validating a topology also performs cracking and clustering of the data. To use a different cluster tolerance than the one specified in the topology, create a copy of the feature class outside of the topology and run the Integrate tool on this data.