public static MapPoint CreateMapPoint( 
   double x,
   double y,
   SpatialReference spatialReference
)

// Use a builder convenience method or use a builder constructor.

MapPoint startPt = MapPointBuilder.CreateMapPoint(1.0, 1.0);
MapPoint endPt = MapPointBuilder.CreateMapPoint(2.0, 1.0);

List<MapPoint> list = new List<MapPoint>();
list.Add(startPt);
list.Add(endPt);

// Builder convenience methods don't need to run on the MCT.
Polyline polyline = PolylineBuilder.CreatePolyline(list, SpatialReferences.WGS84);

// Builder constructors need to run on the MCT.
ArcGIS.Desktop.Framework.Threading.Tasks.QueuedTask.Run(() =>
{
  using (PolylineBuilder pb = new PolylineBuilder(list))
  {
    pb.SpatialReference = SpatialReferences.WGS84;
    Polyline polyline2 = pb.ToGeometry();
  }
});